Biostatistics Decoded 2013 by John Wiley and Sons
Biostatistics is a science that allows us to make abstractions from instantiated facts, therefore helping us to improve our knowledge and understanding of the real world. Most people are aware that biostatistics is concerned with the development of methods and of analytical techniques that are applied to establish facts, such as the proportion of individuals in the general population who have a particular disease. The majority of people are probably also aware that another important application of biostatistics is the identification of relationships between facts, for example, between some characteristic of individuals and the occurrence of disease. Consequently, biostatistics allows us to establish the facts and the relationships among them, that is, the basic building blocks of knowledge. Therefore, it can be said that it is generally recognized that biostatistics plays an important role in increasing our knowledge of medical science, and health professionals in their routine clinical practice make extensive use of statistical information to reason about patients. When considering the likelihood of a given disease, clinicians need to have a lot of information about the clinical picture, diagnostic methods, treatment, prognosis, and prevention of that particular disease. More specifically, physicians use statistical information like the proportion of people in the general population who have that disease (the disease prevalence) or the annual rate of disease episodes (the incidence), the frequency of symptoms and physical signs in that disease (the clinical picture), the proportion of patients that have abnormalities in selected diagnostic tests (the test sensitivity), and the accuracy of each diagnostic test (the test specificity). However, clinical practice is not just involved in understanding the cause of the patients’ complaints. Clinical practice is largely involved in taking action to prevent, correct, remedy, or cure diseases. But before each action is taken, a decision must be made as to whether an action is required and which action will benefit the patient...........................
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